CA 125 Test for Ovarian Cancer

The CA 125 ovarian cancer test is a blood test measures the level of the protein CA 125 in the blood.

This test is part of Cardio-Med's complete physical exam.

Why the Test is Performed

CA 125 is a protein that is found more in ovarian cancer cells than in other cells.

The ovarian cancer test is often used to monitor women who have been diagnosed with ovarian cancer. The ovarian cancer test is useful if the CA 125 level was high when the cancer was first diagnosed. In these cases, measuring the CA 125 over time is a good tool to determine if ovarian cancer treatment is working.

After surgery and chemotherapy, women should have the test every 2 to 4 months for the first 2 years. This is followed by every 6 months for 3 years, and then yearly.

The CA 125 test may also be done if a woman has symptoms or findings on ultrasound that suggest ovarian cancer.

Normal Results

A level above 35 U/mL is considered abnormal.

Normal value ranges may vary slightly among different laboratories. Some labs use different measurements or test different samples. Talk to your physician about the meaning of your specific test results.

What Abnormal Results Mean

In a woman who has ovarian cancer, a rise in CA 125 usually means that the disease has progressed or come back (recurred). A decrease in CA 125 usually means the disease is responding to current treatment.

In a woman who has not been diagnosed with ovarian cancer, a rise in CA 125 may mean a number of things. While it may mean that she has ovarian cancer, it can also indicate other types of cancer, as well as several other diseases, such as endometriosis, which are not cancer.

In healthy women, an elevated CA 125 usually does not mean ovarian cancer is present. Most healthy women with an elevated CA 125 do not have ovarian cancer, or any other cancer.

Any woman with an abnormal CA 125 ovarian cancer test needs further tests. Sometimes surgery is needed to confirm the cause.

We also offer a body scan that provides ultrasound imaging of body organs and a test for stroke to check carotid artery blood flow to the brain. This suite of tests including the physical exam gives your physician a complete view of your state of health.


Call (847)758-1230 today for an appointment and consultation with our physician.
Serving Chicago, IL and all of the Chicago northwest suburbs, southeastern Wisconsin and northwestern Indiana.


Adapted from the U.S. National Library of Medicine, National Institutes of Health

Physical Exam - Level I includes:

  • Prostate Specific Antigen (PSA) Test for prostate cancer
    More . . .
  • CA125 Test for ovarian cancer
    More . . .
Detailed blood pressure evaluation in both arms (seated) and in right arm (recumbent or lying down)      More . . .
Thyroid function profile      More . . .
Resting 12-lead Electrocardiogram (ECG/EKG) recording of electrical activity of the heart      More . . .
Cholesterol/
triglycerides profile      More . . .
Detailed clinical evaluation and consultation by Physician, not Nurse      More . . .
Comprehensive Metabolic Panel      More . . .